Every factual, scientific, or physiological claim in a manuscript gets tiered by evidence strength — claim-by-claim, not file-by-file — before print. A popular claim that doesn't hold up is reported as a finding, never quietly dropped because it's inconvenient.
The same source can support one tier for what it shows in a study, and a different tier for the human claim built on top of it.
Well-replicated human evidence, or genuine consensus.
"Autophagy is a conserved cellular degradation pathway — one of the most solidly established facts in cell biology."
Small trials, mostly animal/mechanistic, mixed human results.
"Nutrient restriction reliably activates autophagy in animal models — strong there, moderate as a basis for human claims."
Hypothesis, or popular claim, weak support. Debunks land here too.
"Autophagy kicks in at 16 hours of fasting" — not supported in humans even at 24 hours.
"I won't drop a claim just because the evidence debunks it — a debunked popular claim is tagged [SPECULATIVE / debunk] and reported as a finding, exactly like a confirmed one, never quietly omitted." The mechanism checking out doesn't rescue the specific number built on top of it.
Where a topic carries real physical risk, contraindications get their own dedicated file, separate from general research, so they can't be diluted.
| Tier | What it means | Example |
|---|---|---|
| ABSOLUTE | Consensus says "do not," not "be careful" | Pregnancy, type 1 diabetes, active eating-disorder history |
| RELATIVE | Possible, but only with clinical screening + monitoring | Daily prescription medication, cardiac risk factors |
For extended fasting, the most dangerous moment is often not the fast itself but the refeeding — reintroducing food too fast can trigger a potentially fatal electrolyte collapse. Naming that explicitly is what a safety file is for.
A blocked tool or an unreadable primary source is normal. Hiding it isn't an option.
SKILL.md lets it auto-discover and trigger from a natural request.No — that's the Research worker's job. This skill tiers and flags claims and sources it's handed or pointed at.
It gets reported anyway, tagged [SPECULATIVE / debunk] — see the refusal gate above. A debunk is a finding, not a loss.
No. ABSOLUTE contraindications never get downgraded to RELATIVE to make a chapter read more permissive.
The file states it plainly at the top, before any finding, and tags every downstream figure as unverified until it's actually checked.